Overview

LFQ-Analyst: An easy-to-use interactive web-platform to analyze and visualize proteomics data preprocessed with MaxQuant.

LFQ-Analyst is an easy-to-use, interactive web application developed to perform differential expression analysis with “one click” and to visualize label-free quantitative proteomic datasets preprocessed with MaxQuant. LFQ-Analyst provides a wealth of user-analytic features and offers numerous publication-quality result output graphics and tables to facilitate statistical and exploratory analysis of label-free quantitative datasets.



Sidebar tabs

  • Analysis: perform your own analysis
  • Demo: familiarise yourself with LFQ-Analyst by browsing through pre-analysed results
  • User Guide: download an in-depth manual

Getting Started

Quick Start

  • Upload your proteinGroups.txt generated by MaxQuant.
  • Upload your experimental design table.
  • Optional: Adjust the p-value cut-off, the log2 fold change cut-off, the imputation type, FDR correction method and/or number of clusters in heatmap in the Advanced Options
  • Press 'Start Analysis'
  • Hint: Use the User Guide tab for a detailed explanation of inputs, advanced options and outputs
  • Note: The experimental design file is not the 'mqpar.xml' file from MaxQuant. Use the example file template provided.



LFQ Results Table

User Guide

LFQ-Analyst: Manual

A detailed user manual can be accessed here.

Contact Us

For any feedback or question regarding LFQ-Analyst, please contact the Monash Proteomics and Metabolomics Facility:

  • Anup Shah: anup.shah(at)monash.edu
  • Ralf Schittenhelm: ralf.schittenhelm(at)monash.edu

How to Cite LFQ-Analyst?

Please Cite: Shah AD, Goode RJA, Huang C, Powell DR, Schittenhelm RB. LFQ-Analyst: An easy-to-use interactive web-platform to analyze and visualize proteomics data preprocessed with MaxQuant. DOI: 0.1021/acs.jproteome.9b00496

News and Updates

  • 24-02-2021: Correlation plot now use all protein expression data
  • 25-11-2020: LFQ-Analyst being accessed by 2000 users worldwide
  • 07-04-2020: LFQ-Analyst being accessed by 1000 users worldwide
  • 03-01-2020: LFQ-Analyst manuscript published in volume 19 of JPR
  • 28-10-2019: LFQ-Analyst paper published online in Journal of Proteome Research (JPR)
  • 02-10-2019: Svg figures download feature added
  • 09-09-2019: Paired test support added
  • 09-09-2019: Option to include single peptide observations in the analysis
  • 19-02-2019: LFQ-Analyst made public


LFQ Results Table